For decades, government, industry, and the mainstream media have extolled the virtues of biotechnology while downplaying its negative side effects. Focusing on agriculture, Resistance Is Fertile challenges this dominant rhetoric by analyzing the major issues around which opponents of biotechnology in Canada are mobilizing resistance – namely, the enclosure of the biological and the knowledge commons, which together form the BioCommons. What emerges is an empirically and theoretically informed analysis of Canada’s regulatory regime, the corporate control of seeds, and attempts to construct and control public discussions about agricultural biotechnology.